China Is Genetically Engineering Mini Pigs To Sell As Pets
We’d all like our baby pets to stay perpetually tiny, but scientists in China are taking that desire to a whole new level.
BGI, a genomics institute located in Shenzhen, announced in late September that it is genetically engineering miniature pigs to sell as pets for $1,600 each.
The institute creates the micropigs by using a gene-editing technique that alters the genomes of a Bama — an already small breed of pig — to make it even smaller. BGI uses TALENs (an enzyme) to disable one of two copies of the growth hormone receptor gene in a Bama’s fetal cells.
BGI then clones pigs from the fetus, which produces stunted male Bama clones that are, in turn, naturally bred with normal females. Half of the resulting offspring are micropigs.
The micropigs were originally used as lab animals that acted as models for human disease, according to Nature magazine. Pigs, specifically smaller breeds of pig, are commonly used as model organisms in biomedical research because they “closely [resemble] man in anatomy, physiology and genetics,” according to the National Center for Biotechnology Information.
According to Yong Li, technical director of BGI’s animal-science platform, BGI has not observed any health problems associated with cloning in any of the gene-edited pigs they’ve produced.
In the future, the institute promises to offer miniature pigs in a variety of coat colors and patterns, which will be achieved through further gene editing.
While BGI feels confident about bringing genetically modified micropigs to the public, other experts remain skeptical.