‘Chromosomal Chaos:’ Complex array of mutations found in rare, aggressive leukemia

Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected. With a poor prognosis and limited options for targeted therapies, this cancer needs new treatment approaches. The team’s results uncover a previously unknown, complex genomic landscape, which can be used to design new personalized drug regimens for SS patients based on their unique genetic makeup. —> Read More