Genomics — The Future of Forensic DNA Profiling

Genomics is the scientific study of the molecular instructions encoded in your cells. It maps your entire genetic structure. Till now, forensic science has focused on only identifying your cell’s nuclei signature — your inner DNA (deoxyribonucleic acid) and, to a degree, your outer miDNA (mitochondrial DNA) — not your genes. The old method of forensically profiling your biological fingerprint by DNA analysis is being replaced by a computerized 3D genome recreation of your entire being.

Genomics is a concept first developed in the 1970’s. It led to the Human Genome Project (HGP) being completed in 2003. The HGP was a massive international research venture that sequenced and mapped all of the human cell genes — together known as the genome. The HGP gave us the ability to read nature’s complete genetic blueprint for building a human being. Like you.

So what’s a genome?

A genome is the whole ensemble of your genetic material. It’s the molecular guide of your DNA, your chromosomes, and your genes that describes how to make your cells. It’s the instruction manual for your body. That book is your genome and the study of that book is termed genomics. It’s pretty much a math exercise. And it’s deadly stuff for identifying criminals with.

Let’s take a quick look at your biology.

Deoxyribonucleic acid is the chemical compound that contains the instructions to develop and direct your life as an organism. DNA molecules are made of two twisting, paired strands, often referred to as a double helix.

Each DNA strand is made of four chemical units, called nucleotide bases, which comprise the genetic “alphabet”. The bases are adenine (A), thymine (T), guanine (G), and cytosine (C). Bases on opposite strands pair specifically — an A always pairs with a T — a C always —> Read More