Hard-to-detect chromosomal anomalies explain neurodevelopmental birth defects

Balanced chromosomal abnormalities (BCAs), a category of structural changes to the human genome, may account for a large portion of birth defects related to brain development and function, according to research presented at the American Society of Human Genetics 2015 Annual Meeting in Baltimore. BCAs are changes to the structure of an individual’s chromosomes, in which one or more fragments of DNA breaks apart from the regions around it and is reattached elsewhere in the genome. —> Read More