Hyperlipidemia, caused by a high-fat diet, aggressively accelerates organ rejection

In two studies published online today in the American Journal of Transplantation, researchers determined that hyperlipidemia accelerates heart-transplant rejection in mice. By using models that mimic the health conditions found in human transplant recipients, the researchers from Tufts determined that transplant rejection was accelerated whether the hyperlipidemia — high cholesterol and high triglycerides in the blood — was caused by genetics or solely by a high-fat diet. —> Read More