iPS cells discover drug target for muscle disease

Duchenne muscular dystrophy (DMD) is disease that leads to the degeneration of muscle due to dysfunctional expression of the protein dystrophin. A new iPS cell model found that the early stages of DMD development can be attributed to a specific family of ion channels that allows an abnormal influx of calcium to enter the cell. This same model can be used for drug discovery to correct the channel behavior. —> Read More