Researchers unravel mysteries of SCN8A mutation in epilepsy

Three studies presented at the American Epilepsy Society’s (AES) 69th Annual Meeting explore the effects of mutations in the SCN8A gene, thought to underlie early infantile epileptic encephalopathy (EIEE) and other neurological conditions. The SCN8A gene mediates electrical signaling in the brain by controlling the flow of sodium currents. Findings from these studies could inform the development of precision medicine therapeutics and lead to more effective strategies for diagnosing and treating patients with epilepsy. —> Read More