Tumor microenvironment of hepatitis B virus-associated hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is intimately associated with a chronically diseased liver tissue, with one of the most prevalent etiological factors being hepatitis B virus (HBV). Transformation of the liver in HBV-associated HCC often follows from long-term symptoms of chronic hepatitis. In a new study, scientists based in China and the US outline HBV’s crucial role in modulating the accumulation of immune cells and fibroblasts, along with cytokines and growth factors, markedly influencing disease progression. —> Read More Here


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